Which demographic factor may increase the risk of contrast-induced nephropathy?

Older age is a significant demographic factor that can increase the risk of contrast-induced nephropathy (CIN). As individuals age, there is typically a decline in renal function due to age-related physiological changes. The kidneys lose some of their ability to filter waste products effectively, and pre-existing conditions such as hypertension or diabetes, which are more prevalent in the elderly population, can further compromise renal function.

When contrast agents are administered, particularly in high doses or in patients with already diminished kidney function, the risk for nephropathy rises. The elderly population often has a combination of reduced glomerular filtration rate (GFR) and potentially other underlying health issues that heighten their susceptibility to the nephrotoxic effects of contrast materials. Consequently, recognizing older age as a risk factor is crucial for clinicians when planning imaging procedures that involve contrast agents, allowing for more informed decision-making and preventive strategies to minimize the risk of CIN.