What is a disadvantage of using aqueous solutions for certain pharmaceuticals?

The correct answer highlights a significant consideration in the formulation of pharmaceuticals. Aqueous solutions, while beneficial for their rapid absorption and ease of administration, can be less stable compared to other forms of medication delivery. The inherent properties of water, such as its ability to facilitate hydrolysis and promote microbial growth, can lead to the degradation of certain drugs when they are dissolved in water. This decreased stability can result in a shortened shelf life and potentially reduced effectiveness of the medication over time. Thus, while they provide immediate benefits for drug delivery, the stability issue poses a challenge for the long-term use and efficacy of these pharmaceuticals.

In contrast, options like rapid metabolism and increased side effects are typically associated with how a drug interacts within the body rather than with the formulation form itself. Higher costs would vary depending on individual drug formulations and manufacturers rather than being an inherent disadvantage of aqueous solutions.